Integrated model of SARS-CoV-2 & the human cell

Integrated model of SARS-CoV-2 & the human cell Homo Sapiens Cellular Overview Carbohydrate Biosynthesis Amino acyl tRNA charging pathway Fatty acid and Lipid Degradation Fatty acid and Lipid Biosynthesis Amino Acid Biosynthesis Amino Acid Degradation Nucleoside Biosynthesis Hormone Biosynthesis Hormone Degradation Cofactor Biosynthesis Nucleoside Degradation Nsp2 Nsp4 Nsp7 Nsp8 Nsp9 Orf8


Bannerman, B. P, Jorge Júlvez, Alexandru Oarga, Tom L Blundell, Pablo Moreno, and R Andres Floto. 'Integrated Human/SARS-CoV-2 Metabolic Models Present Novel Treatment Strategies against COVID-19'. Life Science Alliance 4, no. 10 (1 October 2021): e202000954.

Beaudoin CA, Jamasb AR, Alsulami AF, Copoiu L, van Tonder AJ, Hala S, Bannerman BP, Thomas SE, Vedithi SC, Torres PHM, Blundell TL. Predicted structural mimicry of spike receptor-binding motifs from highly pathogenic human coronaviruses.

Alsulami AF, Thomas SE, Jamasb AR, Beaudoin CA, Moghul I, Bannerman BP, Copoiu L, Vedithi SC, Torres P, Blundell TL. SARS-CoV-2 3D database: understanding the coronavirus proteome and evaluating possible drug targets. Brief Bioinform. 2021 Mar 22;22(2):769-780. doi: 10.1093/bib/bbaa404. PMID: 33416848; PMCID: PMC7929435.